The two were travelling together in a truck from Mozambique to South Africa when they were nabbed at the Lebombo border post near Komatipoort on Monday.
Police spokesperson Brigadier Leonard Hlathi said police and SARS customs officials were conducting their normal duties when a white mini truck pulling a trailer, en route from Mozambique, stopped at the border to be processed.
"The vehicle was searched, and officials discovered makeshift compartments in both the truck and trailer stashed with suspected drugs as well as bottles of illegal liquor.
Preliminary investigation indicates that the occupants were planning to smuggle the drugs from Mozambique into the country before being intercepted," said Hlathi.
Hlathi said law enforcement officers, including soldiers, have been hard at work enforcing lockdown regulations and addressing all crimes in general in Mpumalanga.