Saint Peter's Basilica throws its doors open to visitors on Monday, marking a relative return to normality at the Vatican and beyond in Italy, where most business activity is set to resume.
Italy's lockdown not only extinguished most business activity in the country, but radically disrupted Italians' personal lives, including attending mass.
The Argentine pontiff is not yet expected to lead any public religious ceremonies either in the basilica, which can accommodate 60,000 people, or in Saint Peter's Square, as the Vatican seeks to avoid crowds.
Across Italy's tens of thousands of churches, Catholics will be able to attend not only masses but also weddings and funerals, provided they abide by a series of measures, including wearing masks and sitting or standing well spaced apart.
More than 800,000 commercial activities which have been under lockdown since Prime Minister Giuseppe Conte imposed restrictions on March 9 should be able to reopen on Monday, said Confcommercio, Italy's largest business association.